期刊
JOURNAL OF CLINICAL INVESTIGATION
卷 114, 期 5, 页码 605-610出版社
AMER SOC CLINICAL INVESTIGATION INC
DOI: 10.1172/JCI200422812
关键词
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Cell-to-cell viral transmission facilitates the propagation of HIV-1 and human T cell leukemia virus type 1. Mechanisms of cell-to-cell transmission by retroviruses were not well understood until the recent description of virological synapses (VSs). VSs function as specialized sites of immune cell-to-cell contact that direct virus infection. Deciphering the molecular mechanisms of VS formation provides a fascinating insight into how pathogens subvert immune cell communication programs and achieve viral spread.
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