期刊
JOURNAL OF VIROLOGY
卷 78, 期 17, 页码 9573-9578出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.78.17.9573-9578.2004
关键词
-
类别
资金
- NIAID NIH HHS [R01 AI47770, R21 AI052051, R01 AI052051, R01 AI047770] Funding Source: Medline
The sequence of events leading to human immunodeficiency virus fusion and entry likely involves the recruitment of multiple receptor and coreceptor proteins to a specific complex by the viral envelope. Using fluorescence recovery after photobleaching technology, we find that both CD4 and CCR5 are mobile in the cell membrane. Interestingly, our findings also suggest that the seven-span transmembrane coreceptor is significantly more mobile than CD4 and requires membrane cholesterol for mobility.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据