期刊
FLAVOUR AND FRAGRANCE JOURNAL
卷 19, 期 5, 页码 394-400出版社
WILEY
DOI: 10.1002/ffj.1434
关键词
synthesis; bitter taste; cyclodextrin; cyclodextrin-chitosan adduct; bitter masking
Finding new taste modifiers, particularly bitter-taste blockers (BTBs), is an important goal for pharmaceutical and food industries. Although BTBs have been much sought after, only a few possess a wide spectrum of activity. We prepared, on a gram scale, several macromolecular adducts in which beta- and gamma-CDs are linked to chitosan through succinyl or maleyl bridges. Their bitterness-masking power was evaluated on caffeine and bitter natural extracts (artichoke leaves, aloe and gentian) by a panel test using serial caffeine concentrations as a reference scale. The beta-CD-chitosan adduct showed the highest efficacy and the bitterness attenuation was statistically significant. Copyright (C) 2004 John Wiley Sons, Ltd.
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