期刊
APPLIED PHYSICS LETTERS
卷 105, 期 21, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.4902944
关键词
-
资金
- National Major Research Program of China [2013CB932602]
- Major Project of International Cooperation and Exchanges [2012DFA50990]
- NSFC [51232001, 51172022, 51372020, 51002008]
- Program of Introducing Talents of Discipline to Universities
- Fundamental Research Funds for Central Universities [FRF-SD-12-032A]
- Program for New Century Excellent Talents in University
- Program for Changjiang Scholars and Innovative Research Teams in Universities
We designed and constructed three dimensional (3D) zinc oxide Nanotetrapods (T-ZnOs) modified AlGaAs/GaAs high electron mobility transistors (HEMTs) for enzymatic uric acid (UA) detection. The chemical vapor deposition synthesized T-ZnOs was distributed on the gate areas of HEMTs in order to immobilize uricase and improve the sensitivity of the HEMTs. Combining with the high efficiency of enzyme immobilization by T-ZnOs and high sensitivity from HEMT, the as-constructed uricase/T-ZnOs/HEMTs biosensor showed fast response towards UA at similar to 1 s, wide linear range from 0.2 nM to 0.2 mM and the low detect limit at 0.2 nM. The results point out an avenue to design electronic device as miniaturized lab-on-chip device for high sensitive and specific in biomedical and clinical diagnosis applications. (c) 2014 AIP Publishing LLC.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据