4.4 Article

α-Addition of activated methylenes to alkynoates.: A straightforward synthesis of multifunctional compounds

期刊

TETRAHEDRON LETTERS
卷 45, 期 38, 页码 7035-7038

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2004.07.135

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1,3-dicarbonyl compounds; electrophilic alkyne; nucleophilic alpha-addition; acrylic esters; dihydrothiophene

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The present work describes a simple one pot access to alpha-(gem-difunctional) acrylic esters and to polysubstituted dihydrothiophenes exploiting the addition of activated methylenes to alkynoates rerouted by triphenyl phosphine. (C) 2004 Elsevier Ltd. All rights reserved.

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