期刊
APPLIED PHYSICS LETTERS
卷 104, 期 6, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.4864110
关键词
-
资金
- NIH [R01EB006476, S10 RR022425]
Acoustic droplet vaporization (ADV) is the selective vaporization of liquid microdroplets using ultrasound, resulting in gas bubbles. The ADV process has been proposed as a tool in biomedical applications such as gas embolotherapy, drug delivery, and phase-change contrast agents. Using a 7.5MHz focused transducer, the initial gas nucleus formed in perfluorocarbon microdroplets was directly visualized using ultra-high speed imaging. The experimental results of initial nucleation site location were compared to a 2D axisymmetric linear acoustic model investigating the focal spot of the acoustic wave within the microdroplets. Results suggest a wavelength to droplet diameter dependence on nucleation site formation. (C) 2014 AIP Publishing LLC.
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