期刊
APPLIED PHYSICS LETTERS
卷 103, 期 1, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.4813084
关键词
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资金
- Ministry of Education, Culture, Sports, Science and Technology, Japan [F-12-OS-0016]
- Japan Society for the Promotion of Science (JSPS) KAKENHI [24681032]
- Japan Society for the Promotion of Science (JSPS) through its Funding Program for World-Leading Innovative R&D on Science and Technology
- Grants-in-Aid for Scientific Research [23681031, 25600061, 22246022] Funding Source: KAKEN
Manipulation of particles and molecules in fluid is a fundamental technology in biosensors. Here, we report electrical trapping and identification of single-nanoparticles using a low-aspect-ratio nanopore. Particle trapping and detrapping are implemented through a control of the cross-membrane electrophoretic voltage. This electrical method is found to enable placing an individual nanoparticle in vicinity of a lithographically-defined nanopore by virtue of the balance between the two counteracting factors, electrostatic and electroosmotic forces. We also demonstrate identification of trapped nanoparticles by the ionic current through the particle-pore gap space. This technique may find applications in electrode-embedded nanopore sensors. (C) 2013 AIP Publishing LLC.
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