期刊
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
卷 254, 期 5, 页码 343-346出版社
DR DIETRICH STEINKOPFF VERLAG
DOI: 10.1007/s00406-004-0511-4
关键词
clozapine; schizophrenia; schizoaffective disorder; psychotic bipolar disorder; predictor of response
This study aims at identifying potential predictors of clinical response and functional outcome in 10 1 neuroleptic-refractory patients with a DSM-III-R diagnosis of schizophrenia (N = 34), schizoaffective disorder (N = 30) or bipolar disorder with psychotic features (N = 37), naturalistically treated with clozapine over a 48-month period. The clinical response and functional outcome criteria were respectively defined a priori as: a reduction of at least 50% in the Brief Psychiatric Rating Scale total score in one evaluation with respect to baseline; and a Global Assessment of Functioning Scale score of at least 50. Several clinical and socio-demographic variables were assessed at baseline and only the diagnosis of bipolar disorder was significantly related with the clinical response. Variables significantly related with the functional outcome were female gender, university education and early age at onset.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据