期刊
EXPERT OPINION ON BIOLOGICAL THERAPY
卷 4, 期 10, 页码 1629-1639出版社
ASHLEY PUBLICATIONS LTD
DOI: 10.1517/14712598.4.10.1629
关键词
allergy; bee venom; long synthetic peptides; malaria; Plasmodia; vaccine
This review covers the latest developments of long synthetic peptide technology for the rapid identification and development of malaria vaccine candidates and immunological modulators. A brief description of the two most common solid-phase synthetic procedures, together with the latest advances in optimisation of peptide chain assembly and analytical instrumentation, is given, with special attention to non-specialists. Several examples of vaccine candidates developed in the authors' or their collaborators' laboratories are also provided.
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