期刊
JOURNAL OF BIOSCIENCE AND BIOENGINEERING
卷 98, 期 4, 页码 304-305出版社
SOC BIOSCIENCE BIOENGINEERING JAPAN
DOI: 10.1016/S1389-1723(04)00286-5
关键词
nano-space; chip culture; cell culture
The minimum size of a closed nano-space in which cells can survive was determined using 4-nl nanowells. One or two cells could divide in the nanowell. Our results suggest that the cell division activity in the nano-space is determined by the conflict between intercellular effects and consumption of substrates.
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