The nucleophilic addition reactions of difluorovinyl tosylates with O- and S-nucleophiles

A series of O- and S-nucleophiles reacted with 2,2-difluorovinyl tosylate 1 regiospecitically with the nucleophiles attacking at the terminal CF2 carbon at room temperature, affording alpha,alpha-difluoroethyl ethers or thioethers in moderate to good yields. (C) 2004 Elsevier B.V. All rights reserved.