期刊
APPLIED PHYSICS LETTERS
卷 103, 期 8, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.4818737
关键词
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资金
- excellence cluster 172 Molecular Physiology of the Brain/Microscopy at the Nanometer Range
- Collaborative Research Center 755 Nanoscale Photonic Imaging of the German science foundation (DFG)
- Bernstein Focus for Neurotechnology [01GQ0810]
We present phase contrast x-ray tomography of functional soft tissue within the bony cochlear capsule of mice, carried out at laboratory microfocus sources with well-matched source, detector, geometry, and reconstruction algorithms at spatial resolutions down to 2 mu m. Contrast, data quality and resolution enable the visualization of thin membranes and nerve fibers as well as automated segmentation of surrounding bone. By complementing synchrotron radiation imaging techniques, a broad range of biomedical applications becomes possible as demonstrated for optogenetic cochlear implant research. (C) 2013 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution 3.0 Unported License.
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