期刊
CHEMICAL & PHARMACEUTICAL BULLETIN
卷 52, 期 10, 页码 1231-1234出版社
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.52.1231
关键词
hypervalent iodine reagent; heteropoly acid; spiro compound; C-C coupling; alkaloid
Intramolecular oxidative coupling reaction of N-protected benzyltetrahydroisoquinoline derivatives using hypervalent iodine(III) reagents was investigated. The use of remarkable combination of phenyliodine bis (trifluoroacetate) (PIFA) and heteropoly acid (HPA) in wet acetonitrile smoothly afforded morphinandienone alkaloids, while neospirinedienone alkaloids were obtained in high yield under anhydrous conditions.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据