期刊
JOURNAL OF BIOLOGICAL RHYTHMS
卷 19, 期 5, 页码 400-413出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/0748730404268786
关键词
entrainment; stability; Period gene; BMALl; vasopressin; vasoactive intestinal polypeptide; Cryptochrome; multielectrode; luciferase; fluorescent imaging
资金
- NIMH NIH HHS [MH63104] Funding Source: Medline
The mammalian SCN contains a biological clock that drives remarkably precise circadian rhythms in vivo and in vitro. Recent advances have revealed molecular and cellular mechanisms required for the generation of these daily rhythms and their synchronization between SCN neurons and to the environmental light cycle. This review of the evidence for a cell-autonomous circadian pacemaker within specialized neurons of the SCN focuses on 6 genes implicated within the pacemaking mechanism, an additional 4 genes implicated in pathways from the pacemaker, and the intercellular and intracellular mechanisms that synchronize SCN neurons to each other and to solar time.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据