期刊
APPLIED PHYSICS LETTERS
卷 102, 期 23, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.4809830
关键词
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资金
- Division of Chemical Sciences, Geosciences and Biosciences, Basic Energy Sciences, Office of Science, United States Department of Energy [DE-FC02-04ER15533]
The nitrogen atmospheric pressure plasma jet (APPJ) was applied to induce DNA damage of SCC-25 oral cancer cells. Optical emission spectra were taken to characterize the reactive species produced in APPJ. In order to explore the spatial distribution of plasma effects, cells were placed onto photo-etched grid slides and the antibody H2A.X was used to locate double strand breaks of DNA inside nuclei using an immunofluorescence assay. The number of cells with double strand breaks in DNA was observed to be varied due to the distance from the irradiation center and duration of plasma treatment. (C) 2013 AIP Publishing LLC.
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