期刊
CONTROLLED CLINICAL TRIALS
卷 25, 期 5, 页码 493-501出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cct.2004.07.005
关键词
clinical trial design; cross-over design; parallel design; phase II study
资金
- NCI NIH HHS [CA49764-15] Funding Source: Medline
In this note, we outline the benefits of a partial cross-over design for a class of experiments where the interest is the cumulative effect of dose versus placebo. The goal of our design strategy is to answer several complex question efficiently in a phase II setting with a minimal number of assumptions with an eye towards planning a phase III study. (C) 2004 Elsevier Inc. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据