期刊
BIOLOGICAL CHEMISTRY
卷 385, 期 10, 页码 865-872出版社
WALTER DE GRUYTER GMBH
DOI: 10.1515/BC.2004.113
关键词
cell biology; electron microscopy; pattern recognition; proteomics; structural biology
Cryoelectron tomography opens a window into the inner space of cells. It combines the potential of threedimensional imaging with a closetolife preservation of biological samples. Tomograms with molecular resolution are essentially images of the cellular proteome and, in conjunction with advanced pattern recognition techniques, they can be used to map the molecular landscape inside organelles and cells.
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