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A hypothesis about the role of adult neurogenesis in hippocampal function

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PHYSIOLOGY
卷 19, 期 -, 页码 253-261

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AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00012.2004

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The functional relevance of adult hippocampal neurogenesis has long been a matter of intense experimentation and debate, but the precise role of new neurons has not been sufficiently elaborated. Here we propose a hypothesis in which specific features of newly generated neurons contribute to hippocampal plasticity and function and discuss the most recent and relevant findings in the context of the proposed hypothesis.

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