期刊
PHYTOTHERAPY RESEARCH
卷 18, 期 10, 页码 841-844出版社
WILEY
DOI: 10.1002/ptr.1428
关键词
Dictyophora indusiata; HMF and related analogues; tyrosinase inhibitor; noncompetitive inhibition
The inhibition of mushroom tyrosinase by methanolic extract of Dictyophora indusiata was evaluated and the bioactive component was characterized and identified as 5-(hydroxymethyl)-2-furfural (HMF) by chromatographic and spectroscopic means. Kinetic studies revealed it to be a noncompetitive inhibitor for the oxidation of L-DOPA. On the basis of these findings some related analogues were also tested for their anti-tyrosinase activity, in order to gain more insight into structure and activity relationship among these heterocyclic compounds. Copyright (C) 2004 John Wiley Sons, Ltd.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据