期刊
APPLIED PHYSICS LETTERS
卷 100, 期 11, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.3694928
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资金
- Japanese Society for the Promotion of Science for Young Scientists
- Knowledge Cluster Initiative Second Stage-Tokai Region Nanotechnology Manufacturing Cluster
- Ministry of Education, Culture, Sports, Science and Technology of Japan [21110006]
- Grants-in-Aid for Scientific Research [21110006] Funding Source: KAKEN
Two independent ovarian cancer cell lines and fibroblast controls were treated with nonequilibrium atmospheric pressure plasma (NEAPP). Most ovarian cancer cells were detached from the culture dish by continuous plasma treatment to a single spot on the dish. Next, the plasma source was applied over the whole dish using a robot arm. In vitro cell proliferation assays showed that plasma treatments significantly decreased proliferation rates of ovarian cancer cells compared to fibroblast cells. Flow cytometry and western blot analysis showed that plasma treatment of ovarian cancer cells induced apoptosis. NEAPP could be a promising tool for therapy for ovarian cancers. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.3694928]
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