期刊
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
卷 18, 期 5, 页码 1039-+出版社
W B SAUNDERS CO
DOI: 10.1016/j.hoc.2004.06.007
关键词
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资金
- NCI NIH HHS [R01 CA106633-01, R01 CA106633-03, R01 CA106633-04, P30CA56036-03, R01 CA106633-02, R01 CA106633] Funding Source: Medline
Radiotherapy is one of the most widely used treatments for cancer; however, the development of tumor radioresistance is an ongoing problem. Agents that target tumor angiogenesis are being used in combination with radiotherapy to improve the therapeutic index without a clear understanding of how these agents may affect radiosensitization. This article discusses recently published studies that may shed some light on the underlying signaling mechanisms that are involved in the interactions of antiangiogenic agents with ionizing radiation.
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