期刊
MICROBES AND INFECTION
卷 6, 期 12, 页码 1110-1116出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.micinf.2004.05.025
关键词
major histocompatibility complex (MHC); parasites; host-parasite coevolution; balancing selection; heterozygote advantage; mate choice
Overdominant selection or heterozygote advantage can partly explain the extraordinary polymorphism found at classical major histocompatibility complex (MHC) loci. However, several studies employing only single infectious agents often failed to detect it. Here, we review recent studies suggesting that due to the dominant nature of MHC-mediated resistance, a heterozygote advantage is most likely to be detected in multiple pathogen challenges. (c) 2004 Elsevier SAS. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据