期刊
PHYTOCHEMISTRY
卷 65, 期 20, 页码 2789-2796出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.phytochem.2004.08.024
关键词
Calophyllum inophyllum; Clusiaceae; roots; nut; xanthones; triterpene; phenylpyranocoumarins; inoxanthone; cytotoxicity; antibacterial activity
The study of the chemical constituents of the root bark and the nut of Calophyllum inophyllum has resulted in the isolation and characterization of a xanthone derivative, named inoxanthone, 3, together with 12 known compounds: caloxanthones A, 4 and B, 5, macluraxanthone, 6, 1,5-dihydroxyxanthone, 7, calophynic acid, 8, brasiliensic acid, 9 inophylloidic acid, 10, friedelan-3-one, 11, calaustralin, 12, calophyllolide, 13, inophyllums, C, 14 and E, 15. Their structures were established on the basis of spectral evidence. Their in vitro cytotoxicity against the KB cell line and their antibacterial activity and potency against a wide range of micro organisms were evaluated. (C) 2004 Elsevier Ltd. All rights reserved.
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