期刊
JOURNAL OF NEUROSCIENCE
卷 24, 期 42, 页码 9244-9249出版社
SOC NEUROSCIENCE
DOI: 10.1523/JNEUROSCI.3339-04.2004
关键词
adhesion; axon terminal; dendrite; neuron; synapse; synaptogenesis
Neuronal transmission relies on signals transmitted through a vast array of excitatory and inhibitory neuronal synaptic connections. How do axons communicate with dendrites to build synapses, and what molecules regulate this interaction? There is a wealth of evidence suggesting that cell adhesion molecules (CAMs) provide much of the information required for synapse formation. This review highlights the molecular mechanisms used by CAMs to regulate presynaptic and postsynaptic differentiation.
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