期刊
JOURNAL OF CELL BIOLOGY
卷 167, 期 2, 页码 203-207出版社
ROCKEFELLER UNIV PRESS
DOI: 10.1083/jcb.200408047
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- NIAMS NIH HHS [R01 AR027883, R01-AR27883] Funding Source: Medline
For many years after the discovery of actin filaments and microtubules, it was widely assumed that their polymerization, organization, and functions were largely distinct. However, in recent years it has become increasingly apparent that coordinated interactions between microtubules and filamentous actin are involved in many polarized processes, including cell shape, mitotic spindle orientation motility, growth cone guidance, and wound healing. In the past few years, significant strides have been made in unraveling the intricacies that govern these intertwined cytoskeletal rearrangements.
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