期刊
APPLIED PHYSICS LETTERS
卷 100, 期 12, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.3693165
关键词
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资金
- Bioelectrics Inc. (USA)
- MST
- Fundamental Research Funds for the Central Universities and Technology Cooperation [2009DFB30370]
- National Basic Research Program [2007CB935602]
With the development of plasma medicine, safety issues are emerging as a serious concern. In this study, both intracellular (genetic engineering) and extracellular (scavengers) measures were tested in an effort to determine the best protection for cells against plasma-induced oxidative stress. All results of immediate reactive species detection, short term survival and long term proliferation, suggest that intracellular pathways are superior in reducing oxidative stress and cell death. This work provides a potential mechanism to enhance safety and identifies precautionary measures that should be taken in future clinical applications of plasmas. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.3693165]
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