期刊
PANCREAS
卷 29, 期 4, 页码 291-297出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00006676-200411000-00008
关键词
pancreatitis; extrapancreatic; African American; Hispanic
资金
- NCRR NIH HHS [G12-RR03026] Funding Source: Medline
- NIMHD NIH HHS [P20MD00182] Funding Source: Medline
Objective: Many studies have been published on acute pancreatitis but few, if any, on extrapancreatic manifestations (EPM) in African Americans and Hispanics. We studied the effect of EPM on mortality in these 2 ethnic groups. Methods: Records of 760 acute pancreatitis patients ( 417 African-American and 343 Hispanic), ages 19 - 85 years, over a 15-year period were reviewed retrospectively. Data were analyzed for EPM and mortality. Results: Of the 760 patients, alcohol use was identified as the etiology in 53% of cases and gallstones in 42%. EPM were present in 148 patients (19.5%). Gastrointestinal bleeding (22%) was the most common EPM. Patients with EPM did not differ from patients without EPM on demographics or acute pancreatitis - related variables ( P > 0.05). Patients with EPM had higher odds of having comorbidity relative to patients without EPM ( OR = 2.9, CI = 2.0 - 4.2). Of 760 patients, 109 died (14%). However, mortality was significantly higher (26%) in patients with EPM in comparison to those without EPM (11%), P = 0.001. Controlling for other variables, patients with EPM had higher odds of mortality relative to patients without EPM ( OR = 2.8, CI = 1.7 - 4.4). Conclusion: Mortality was high in our patients compared with the literature (5% - 10%). EPM increased the mortality significantly ( 26%).
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