期刊
NATURE GENETICS
卷 36, 期 11, 页码 1133-1137出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/ng1104-1133
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资金
- NHLBI NIH HHS [R01 HL073760] Funding Source: Medline
- NIAAA NIH HHS [P60 AA010760] Funding Source: Medline
The goal of the Complex Trait Consortium is to promote the development of resources that can be used to understand, treat and ultimately prevent pervasive human diseases. Existing and proposed mouse resources that are optimized to study the actions of isolated genetic loci on a fixed background are less effective for studying intact polygenic networks and interactions among genes, environments, pathogens and other factors. The Collaborative Cross will provide a common reference panel specifically designed for the integrative analysis of complex systems and will change the way we approach human health and disease.
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