期刊
NATURE REVIEWS MICROBIOLOGY
卷 2, 期 11, 页码 898-907出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrmicro1021
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Gastrointestinal pathogens are faced with an extremely acidic environment. Within moments, a pathogen such as Escherichia coli O157:H7 can move from the nurturing pH 7 environment of a hamburger to the harsh pH 2 milieu of the stomach. Surprisingly, certain microorganisms that grow at neutral pH have elegantly regulated systems that enable survival during excursions into acidic environments. The best-characterized acid-resistance system is found in E. coli.
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