期刊
FEMS MICROBIOLOGY LETTERS
卷 240, 期 1, 页码 105-110出版社
OXFORD UNIV PRESS
DOI: 10.1016/j.femsle.2004.09.027
关键词
antimicrobial peptides; cathelicidins; transmission electron microscopy; atomic force microscopy; ovine blood
类别
The effect of two ovine-derived peptides on the morphology of Staphylococcus aureus NCTC 4163 cells were investigated using transmission electron microscopy and atomic force microscopy. Both techniques showed that SMAP29, an alpha-helical peptide, induced cell lysis, whereas OaBac5mini, a proline/arginine-rich peptide, caused no observable morphological changes. This is consistent with previous experimental work which indicated that SMAP29 caused cell death and induced cell lysis, whereas OaBac5mini acted by interacting with the inner cellular contents. (C) 2004 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.
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