期刊
APPLIED PHYSICS LETTERS
卷 99, 期 19, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.3660581
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资金
- Leverhulme Foundation [F00276M]
- Smoking Research Foundation
- Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan
- Grants-in-Aid for Scientific Research [22760207] Funding Source: KAKEN
We report a single-molecule-based analysis of strand breakages on large DNA molecules induced by an atmospheric pressure plasma jet. We exposed DNA solution to an argon plasma jet; single-molecule observation that involved molecular combing was then used to measure the length of individual DNA molecules. The measured DNA length showed that plasma exposure caused a marked change in length of DNA molecules. The rate of plasma-induced strand breakage on large random-coiled DNA molecules was determined using a simple mathematical model. For strand breaks on large DNA molecules the rate was estimated. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3660581]
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