期刊
GENOME RESEARCH
卷 14, 期 11, 页码 2308-2318出版社
COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
DOI: 10.1101/gr.2523904
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资金
- MRC [MC_U117532067] Funding Source: UKRI
- Medical Research Council [MC_U117532067] Funding Source: Medline
- NCRR NIH HHS [M01 RR00833, M01 RR000833] Funding Source: Medline
- Medical Research Council [MC_U117532067] Funding Source: researchfish
To investigate the role of post-transcriptional controls in the regulation of protein expression for the malaria parasite, Plasmodium falciparum, we have compared mRNA transcript and protein abundance levels for seven different stages of the parasite life cycle. A moderately high positive relationship between mRNA and protein abundance was observed for these stages; the most common discrepancy was a delay between mRNA and protein accumulation. Potentially post-transcriptionally regulated genes are identified, and families of functionally related genes were observed to share similar patterns of mRNA and protein accumulation.
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