期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 48, 期 11, 页码 4485-4487出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.48.11.4485-4487.2004
关键词
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A simple, nonisotopic, semiautomated bioassay for the measurement of antimalarial drug levels in plasma or serum based on the quantitation of histidine-rich protein II in malaria culture is presented. The assay requires only small sample volumes and was found to be highly sensitive and reproducible. The results closely paralleled those obtained with isotopic bioassays (R = 0.988, P < 0.001) and high-performance liquid chromatography-electrochemical detection (R = 0.978, P < 0.001).
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