4.6 Article

Single cell manipulation using ferromagnetic composite microtransporters

期刊

APPLIED PHYSICS LETTERS
卷 96, 期 4, 页码 -

出版社

AMER INST PHYSICS
DOI: 10.1063/1.3293457

关键词

biomedical materials; cellular biophysics; composite materials; ferromagnetic materials; iron compounds; microfabrication; microfluidics; microorganisms

资金

  1. National Science Foundation CAREER [CMMI-0745019]
  2. NSF [CBET-0828167]
  3. ARO MURI SWARMS [W911NF]
  4. Div Of Civil, Mechanical, & Manufact Inn
  5. Directorate For Engineering [0745019] Funding Source: National Science Foundation

向作者/读者索取更多资源

For biomedical applications, such as single cell manipulation, it is important to fabricate microstructures that can be powered and controlled wirelessly in fluidic environments. In this letter, we describe the construction and operation of truly micron-sized, biocompatible ferromagnetic microtransporters driven by external magnetic fields. Microtransporters were fabricated using a simple, single step fabrication method and can be produced in large numbers. We demonstrate that they can be navigated to manipulate single cells with micron-size precision without disturbing the local environment.

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