期刊
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
卷 89, 期 11, 页码 5517-5522出版社
ENDOCRINE SOC
DOI: 10.1210/jc.2004-0480
关键词
-
资金
- NIA NIH HHS [K01-AG-00685, K01-AG-00747, P30-AG-21332, P60-AG-12583, R01-AG-19310, R01-AG/DK-20583, R29-AG-14066] Funding Source: Medline
The purpose of this study was to investigate whether aerobic fitness, body composition, body fat distribution, and inflammation are different in obese postmenopausal women with and without the metabolic syndrome (MS), and whether the severity of MS is associated with these characteristics. Fifty-eight women (age, 59+/-1 yr; body mass index, 33.0+/-0.6 kg/m(2)) completed testing of maximal aerobic capacity, body composition (fat mass, lean mass, and percent body fat), body fat distribution (sc and visceral fat areas, and regional adipocyte sizes), and inflammation (C-reactive protein, IL-6, and TNF-alpha, and their soluble receptors). Lean mass (44.4+/-0.9 vs. 41.2+/-0.9 kg; P<0.05), visceral fat area (180 +/- 10 vs. 135 +/- 7 cm(2); P<0.001), and plasma soluble TNF receptor 1 (sTNFR1; 860+/-25 vs. 765+/-42 pg/ml; P<0.05) were higher in women with the MS (n=27) than in those without the MS (n=31). The number of MS components was directly related to weight, body mass index, fat mass, lean mass, visceral fat area, and plasma sTNFR1. We conclude that obese older women with the MS are characterized by high lean mass, high visceral fat, and elevated sTNFR1, and the severity of the MS is associated with body composition, visceral adiposity, and inflammation.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据