期刊
NEUROLOGY
卷 63, 期 10, 页码 1944-1946出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1212/01.WNL.0000144341.16830.01
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Identification of new optic pathway tumors (OPTs) and progression of pre-existing OPTs in children with neurofibromatosis 1 (NF1) have been reported infrequently after age 6. The authors present eight children with NF1 ( mean age 12.2 years) seen in three NF1 centers who had either late-onset ( four of eight) or late-progressive ( seven of eight) OPT. Continued monitoring of individuals with NF1 into adulthood for the development of OPTs and for progression of known OPTs is warranted.
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