期刊
APPLIED PHYSICS LETTERS
卷 94, 期 5, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.3076127
关键词
biosensors; DNA; microfluidics; proteins; surface acoustic wave transducers
资金
- Engineering and Physical Sciences Research Council (U.K.)
- EPSRC [EP/E015530/1] Funding Source: UKRI
- Engineering and Physical Sciences Research Council [GR/S51417/01, EP/C006755/1, GR/S51486/01, GR/S51493/01, EP/E015530/1] Funding Source: researchfish
The two-dimensional concentration and manipulation of micron-scale particles by orthogonal, surface acoustic, standing waves is demonstrated. The particles are organized by liquid pressure waves in a microfluidic system over a piezoelectric substrate and form a uniform two-dimensional array with a spacing governed by the mechanical nodes of the two orthogonal, surface acoustic, standing waves. The nodal spacing can be controlled in each orthogonal direction independently by adjustment of the radio frequency applied to the separate acoustic wave transducers. This technique could be used to enhance the particle concentrations at sensing locations in DNA or protein array detectors.
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