期刊
APPLIED PHYSICS LETTERS
卷 95, 期 7, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.3211328
关键词
biochemistry; bioelectric phenomena; biosensors; carbon nanotubes; molecular biophysics; molecular configurations; proteins
资金
- Nanyang Technololgical University School of Materials Science and Engineering
- Institute of Materials Research and Engineering
Detailed understanding of interaction between biomolecules and single-walled carbon nanotubes (SWCNTs) is important in the design and applications of biosensors that employ SWCNTs for transduction of the analytes response. Reciprocal interactions of SWCNT with bovine serum albumin are investigated here with pristine and carboxylated nanotubes. Carboxylic functionalization was found to inflict a deeper change on protein conformation, than their pristine counterparts, accompanied with a change in nanotube conductance. This observation has significant implications for biosensors in highlighting the need to take into account the surface functionalization state of the active materials.
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