4.6 Article

Prevention of Intraventricular Hemorrhage by Indomethacin in male preterm infants

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JOURNAL OF PEDIATRICS
卷 145, 期 6, 页码 832-834

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MOSBY-ELSEVIER
DOI: 10.1016/j.jpeds.2004.07.035

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  1. NCRR NIH HHS [RR-06022] Funding Source: Medline
  2. NINDS NIH HHS [NS-35476, NS-27116] Funding Source: Medline

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Our multicenter Indomethacin Intraventricular Hemorrhage (IVH) Prevention Trial demonstrated a reduction of lVH in preterm infants. Analysis of our cohort by sex showed indomethacin halved the incidence of lVH, eliminated parenchymal hemorrhage, and was associated with higher verbal scores at 3 to 8 years in boys.

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