期刊
CURRENT OPINION IN CELL BIOLOGY
卷 16, 期 6, 页码 700-707出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2004.09.004
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To what extent are the pathways that regulate self-renewal conserved between stem cells at different stages of development and in different tissues? Some pathways play a strikingly conserved role in regulating the self-renewal of diverse stem cells, whereas other pathways are specific to stem cells in certain tissues or at certain stages of development. Recent studies have highlighted differences between the self-renewal of embryonic, fetal and adult stem cells. By understanding these similarities and differences we may come to a molecular understanding of how stem cells replicate themselves and why aspects of this process differ between stem cells.
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