期刊
INFECTION AND IMMUNITY
卷 72, 期 12, 页码 7330-7333出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.72.12.7330-7333.2004
关键词
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In Candida albicans, calcineurin is essential for virulence and survival during membrane perturbation by azoles. Crz1 is a proposed downstream target of calcineurin based on studies of Saccharomyces cerevisiae. However, the in vitro phenotypes of C. albicans crz1/crz1 and calcineurin mutants differ and Crz1 is not required for virulence.
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