期刊
APPLIED PHYSICS LETTERS
卷 93, 期 11, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.2987484
关键词
-
资金
- SRU Biosystems
A replica-molded plastic-based vertically emitting distributed feedback (DFB) laser has been demonstrated for label-free chemical and biomolecular detection in which the emission wavelength is modulated by changes in bulk and surface-adsorbed material permittivity. A one-dimensional surface grating formed in UV-curable polymer on a flexible plastic substrate is coated with a thin polymer film incorporating organic laser dye. When optically pumped with a similar to 10 ns pulse at lambda=532 nm, the DFB laser exhibits stimulated emission in the lambda=585-620 nm wavelength range with a linewidth as narrow as delta lambda=0.09 nm. While exposed to chemical solutions with different refractive indices and adsorbed charged polymer monolayers, the laser sensor demonstrates single mode emission over a tuning range of similar to 14 nm and the ability to perform kinetic monitoring of surface-adsorbed mass. A protein-protein interaction experiment is used to demonstrate the capability to characterize antibody-antigen affinity binding constants. (C) 2008 American Institute of Physics.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据