期刊
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
卷 19, 期 6, 页码 467-473出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14756360412331280491
关键词
microwave chemistry; imino-1,2,3-dithiazoles; Appel salt; carbazoles; thiazoles; cytotoxic and antiproliferative activities
Novel 6-substituted thiazolocarbazole derivatives have been synthesized under microwave irradiation via the corresponding imino-1,2,3-dithiazoles. In vitro antitumor potential of these polyheterocyclic compounds was evaluated. Among all the tested thiazolocarbazoles, compound 10 is the most effective in inhibiting cell growth.
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