期刊
CURRENT OPINION IN GENETICS & DEVELOPMENT
卷 14, 期 6, 页码 620-626出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.gde.2004.09.007
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In the past two years, new data on conceptual aspects of the evolution of eukaryotic genome size have appeared, including the adaptivity of genome enlargement, the mechanisms of genome size change and the relation of genome size to organismal complexity. New data on the hypotheses of 'selfish DNA' and 'mutational equilibrium' have been recently obtained. A relationship is emerging between the intragenomic distribution of noncoding DNA and differential gene expression, which suggests that noncoding DNA is involved in epigenetic organization of the genome and organismal complexity. The standpoint of dynamical chaos, which integrates multilevel selection and mutation biases, may provide a framework for studying the evolution of genome size.
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