期刊
PROTEIN AND PEPTIDE LETTERS
卷 11, 期 6, 页码 515-519出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/0929866043406193
关键词
HMG-17; histone H1; quantification; ELISA; tissue distribution
HMG-17 proteins are nucleosomal proteins, implicated in control of chromatin structure and transcription, in a way that has not yet been fully understood. In this report, quantification of HMG-17 in porcine tissues was performed, by ELISA, using previously produced and characterized specific rabbit anti-HMG-17 antibodies. Our results showed high levels of HMG-17 compared to the DNA and H1 content of the tissues (on the contrary to previous reports), and more specifically that there were 1.7 molecules of HMG-17 per molecule of histone H1.
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