期刊
BIOINFORMATICS
卷 20, 期 18, 页码 3643-3646出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/bth397
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- NLM NIH HHS [R01-LM007938] Funding Source: Medline
Given the positions of protein-coding genes along genomic sequence and probability values for protein alignments between genes, DAGchainer identifies chains of gene pairs sharing conserved order between genomic regions, by identifying paths through a directed acyclic graph (DAG). These chains of collinear gene pairs can represent segmentally duplicated regions and genes within a single genome or syntenic regions between related genomes. Automated mining of the Arabidopsis genome for segmental duplications illustrates the use of DAGchainer.
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