期刊
JOURNAL OF ORGANOMETALLIC CHEMISTRY
卷 690, 期 1, 页码 151-156出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.jorganchem.2004.09.002
关键词
organoantimony; arylhydroxamic acid; crystal structures; antitumor activity
A series of novel organoantimony arylhydroxamates with the formulae [Ar3SbL2,](-)[HNEt3](+) (LH = arylhydroxamic acid: Ar = C6H5. 4-CH3C6H4, 3-CH3C6H4, 4-ClC6H4, 4-FC6H4) and (4-CH3C6H4)(4)SbL were synthesized and characterized by elemental analysis, IR. H-1 NMR and mass spectroscopy. The crystal structures of (4-CH3C6H4)(4)SbL and [Ph3SbL2](-)[HNEt3](+) were determined by X-ray diffraction. The in vitro antitumor activities of all compounds against three human cancer cells are reported. (C) 2004 Published by Elsevier B.V..
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