期刊
SCIENCE
卷 307, 期 5706, 页码 108-110出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1101675
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资金
- FIC NIH HHS [TW005673] Funding Source: Medline
- NIGMS NIH HHS [GM64590] Funding Source: Medline
We report a genome-wide search of Y-linked genes in Drosophila pseudoobscura. All six identifiable orthologs of the D. melanogaster, Y-linked genes have autosomal inheritance in D. pseudoobscura. Four-orthologs were investigated in detail and proved to be Y-linked in D. guanche and D. bifasciata, which shows that less than 18 million years ago the ancestral Drosophila Y chromosome was translocated to an autosome in the D. pseudoobscura lineage. We found 15 genes and pseudogenes in the current Y of D. pseudoobscura, and none are shared with the D. melanogaster Y. Hence, the Y chromosome in the D. pseudoobscura lineage appears to have arisen de novo and is not homologous to the D. melanogaster Y.
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