Desmethylubiquinone Q2 from the Far-Eastern ascidian Aplidium glabrum:: structure and synthesis

Two new diprenylquinones, glabruquinone A (desmethylubiquinone Q(2)) having cancer preventive properties and its minor isomer Glabruquinone B were isolated from the ascidian Aplidium glabrum. Their structures have been elucidated by NMR and mass spectra and confirmed by synthesis. (C) 2004 Elsevier Ltd. All rights reserved.