期刊
MAGNETIC RESONANCE IN MEDICINE
卷 53, 期 2, 页码 465-469出版社
JOHN WILEY & SONS INC
DOI: 10.1002/mrm.20367
关键词
in vivo MR spectroscopic imaging; brain; instrumental instabilities; frequency drift; EPSI
资金
- NIBIB NIH HHS [EB00730, R01 EB000730] Funding Source: Medline
Spectral quality in H-1 magnetic resonance spectroscopic imaging (MRSI) critically depends on the stability of the main magnetic field. For echo-planar MRSI implemented at 3 T, temperature variation in the passive steel shims of the magnet system can lead to a significant drift in the resonance frequency. A method is presented that incorporates interleaved measurement of the instantaneous resonance frequency of a reference water signal into a volumetric MRSI sequence and allows correction for the drift during postprocessing. Results from normal human brain at 3 T indicate that the correction largely removes lineshape distortions, recovers metabolite signal loss, and improves spectral quality by reducing the width of spectral lines; however, particularly in inferior regions, other sources of distortion may be present that cause broadening of spectral lines. (C) 2005 Wiley-Liss, Inc.
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